Sugammadex Versus Neostigmine for Postoperative Nausea and Vomiting After Laparoscopic Gynaecological Surgery
Status:
Completed
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
The laparoscopic technique is commonly employed for abdominal gynaecological surgery in
women. Postoperative nausea and vomiting (PONV) may occur in 30% of women undergoing
gynaecological surgery. In patients with multiple risk factors for nausea and vomiting, the
incidence is up to 80%. PONV has a significant negative effect on patient satisfaction after
anesthesia and is one of the most common causes for unexpected hospital admissions in
day-surgery.
Sugammadex and Neostigmine are both drugs that are used to reverse the effect of muscle
relaxation producing drugs that are commonly used during surgery. Neostigmine has been the
drug of common use for this purpose, but PONV is reported with its usage.
With this research we intend to determine whether the trial drug Sugammadex would reduce the
incidence of PONV in high-risk women after undergoing laparoscopic gynaecological surgery
when compared to Neostigmine.