Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage

• Status: Completed
• Trial end date: 2017-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this work is to compare the effectiveness of vaginal versus sub-lingual misoprostol for medical treatment of first trimester missed miscarriage.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• All women above 18 years of age

• Less than 12 weeks of gestation.

• Pregnancy is confirmed by pregnancy test or ultrasound scan.

• missed abortion

• Normal general and gynecological examination.

• The size of the uterus on pelvic examination was compatible with the estimated duration of pregnancy

Exclusion Criteria:

• Hemodynamically unstable.

• Suspected sepsis with temperature 38 °C.

• Concurrent medical illness e.g. hematological, cardiovascular, thromboembolism, respiratory illnesses, recent liver disease or pruritus of pregnancy.

• Presence of intrauterine contraceptive device (IUCD).

• Suspect or proven ectopic pregnancy.

• Failed medical or surgical evacuation before presentation.

• Known allergy to misoprostol.