Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens
Status:
Unknown status
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
This trial is designed to assess if there is evidence of subclinical joint bleeding on
MRI/X-Ray in adults with severe Haemophilia A while on standard and/or pharmacokinetically
tailored prophylaxis regimens. Participants with severe Haemophilia A will have longitudinal
MRI and XRay imaging of their elbows, ankles and knees at 0, 6 and 18 months while on
standard ( 0-6 months) and then pharmacokinetically tailored (7-18 months) recombinant Factor
VIII prophylaxis.