Study to Reveal if Fibrinogen Treatment Effects Blood Clotting Better Than a Platelet Transfusion

• Status: Completed
• Trial end date: 2014-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients with need of platelet transfusion for any reason will participate in this study. Directly before the start of infusion and one hour after the end of platelet transfusion blood samples will be drawn and treated with different concentrations of Fibrinogen (a blood clotting factor) in-vitro. Blood samples with and without Fibrinogen/platelet transfusion will be compared. The study hypothesis is that treatment with Fibrinogen results in a better stabilisation of blood coagulation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University Innsbruck

Criteria

Inclusion Criteria:

• patient with the clinical need for platelet transfusion

• age: 18 - 85 years

Exclusion Criteria:

• pregnant or nursing women

• patients who disagree to participate in the study

• for emergency patients: patients with known refusal of a participation in this clinical trial

• active participation in a clinical trial

• any condition, including the presence of laboratory abnormalities, which would place confound in the ability to interpret data from the study

• any serious medical condition, laboratory abnormalities, or psychiatric illness, that would prevent the subject from signing the informed consent form