Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer
Status:
Completed
Trial end date:
2021-08-07
Target enrollment:
Participant gender:
Summary
This is a 2-phase study in participants with advanced solid tumors. The first phase consists
of Part A and Part B. Part A will investigate the effect of rifampin on the pharmacokinetics
(PK) of pamiparib and Part B will investigate the effect of itraconazole in the PK of
pamiparib. Phase 2 will allow participants continued access to pamiparib after the PK phase
and will provide additional safety data.