Study to Investigate the Effect of Formoterol vs Salmeterol on Small Airways Physiological Parameters in COPD Patients

• Status: Completed
• Trial end date: 2012-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a crossover Study to investigate the effect of Formoterol versus Salmeterol on small airways physiological parameters in COPD patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chiesi Farmaceutici S.p.A.
• Treatments: Formoterol Fumarate; Salmeterol Xinafoate

Criteria

Inclusion Criteria:

• Patients with a clinical diagnosis of COPD

• Post bronchodilator FEV1 between 30% and 80% predicted values at screening

• Post-bronchodilator FEV1/FVC < 0.7

Exclusion Criteria:

• Positive FEV1 reversibility test: FEV1 change greater than 200 mL and 12%

• History of another medical condition contraindicating participation in the study

• Clinical evidence of heart failure