Overview

Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Status:
Completed

Trial end date:
2020-08-21

Target enrollment:

Participant gender:

Summary

To assess the effect of a single dose of aluminum hydroxide/magnesium hydroxide/simethicone and omeprazole on the pharmacokinetics (PK) of TBPM, following a single dose of TBPM-PI-HBr in healthy adult subjects.

Phase:

Phase 1

Details

Lead Sponsor:

Spero Therapeutics

Treatments:

Aluminum Hydroxide
Aluminum hydroxide, magnesium hydroxide, drug combination
Aluminum hydroxide, magnesium hydroxide, simethicone drug combination
Magnesium Hydroxide
Omeprazole
Simethicone
TEMPO