Overview

Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults

Status:
RECRUITING

Trial end date:
2025-09-30

Target enrollment:

Participant gender:

Summary

This is a Phase 1, open-label, 2-part study to evaluate the effect of multiple doses of oral carbamazepine or oral itraconazole on the plasma pharmacokinetic profile of radiprodil in healthy adult participants. In addition, the safety and tolerability of radiprodil given together with oral carbamazepine or itraconazole will be assessed.

Phase:

PHASE1

Details

Lead Sponsor:

GRIN Therapeutics, Inc.

Collaborator:

Avance Clinical Pty Ltd.

Treatments:

Carbamazepine
Itraconazole
radiprodil