Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia

• Status: Unknown status
• Trial end date: 2019-12-31
• Target enrollment: 0
• Participant gender: All

Summary

What is the optimal maintenance dose of remifentanil to ensure apnoea, during breath hold episodes in children having cardiac MR imaging with general anaesthesia?

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alder Hey Children's NHS Foundation Trust
• Treatments: Propofol; Remifentanil

Criteria

Inclusion Criteria:

• Children of one year (of age) or older and younger than 7 years of age.

• Scheduled for cardiac MR imaging under general anaesthesia at Alder Hey Children's Hospital.

• Parental Consent

Exclusion Criteria:

• Hypersensitivity to any study drug

• Known abnormal response to opiate analgesics or co-morbidity associated with abnormal central control of breathing

• Families unable to understand or complete consent

• Any other contraindication to proposed anaesthetic technique: at the discretion of the responsible anaesthetist.

• Documented significant renal or hepatic dysfunction