Study to Evaluate the Fecal Microbiota Transplantation (FMT) in the Treatment of Ulcerative Colitis
Status:
Not yet recruiting
Trial end date:
2027-04-15
Target enrollment:
Participant gender:
Summary
The study is to evaluate the safety, feasibility, and preliminary efficacy of frozen FMT
delivery via retention enema compared to lyophilized powder given in oral capsules as
induction FMT in subjects with active UC. This study will also determine changes in
microbiome (diversity and genera) and proportion of antibody-coated microbiota from baseline
to after completion of FMT.
Phase:
Phase 1
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston