Study to Evaluate the Efficacy and Safety of Minocycline in Angelman Syndrome

• Status: Completed
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

RANDOMIZED CLINICAL TRIAL, PLACEBO COMPARED TO EVALUATE THE EFFICACY AND SAFETY OF MINOCYCLINE IN ANGELMAN SYNDROME (A-MANECE STUDY)

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Puerta de Hierro University Hospital
• Treatments: Minocycline

Criteria

Inclusion Criteria:

• Male or female between 6 and 30 years old.

• Clinical diagnosis of Angelman Syndrome and molecular confirmation of diagnosis.

• The participant has an acceptable guardian can give consent on behalf of the participant.

Exclusion Criteria:

• Patients with hypersensitivity to tetracyclines.

• Patients with impaired hepatic or renal function and in those with mainly drug allergy history.

• Any other condition that in the opinion of the investigator is considered clinically relevant and that administration of minocycline contraindicated