Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After Transplantation

• Status: Completed
• Trial end date: 2012-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This blinded, placebo-controlled study will administer inhaled nitric oxide to patients undergoing liver transplantation. The purpose of the study is to test if inhaled nitric oxide prevents liver injury associated with the restoration of blood flow. The premise of the current study is provided by previous studies which document a protective effect of inhaled nitric oxide in this clinical setting.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Alabama at Birmingham
• Collaborators: Mallinckrodt; University of Washington
• Treatments: Nitric Oxide

Criteria

Inclusion Criteria:

• Patients > 19 yr of age scheduled to undergo liver transplantation.

Exclusion Criteria:

• Patients < 19 yr of age

• Patients undergoing re-transplantation or dual organ transplantation

• Patients with underlying pulmonary complications