Overview
Study to Evaluate Safety and Immunologic Biomarker of Rapamune in Patients With Stable Renal Transplant Recipient
Status:
Unknown status
Unknown status
Trial end date:
2013-12-01
2013-12-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
For patients who meet the inclusion criteria and who agree to participate in this study, the investigators sampled peripheral blood 10cc and performed the analysis for immunologic profile just before the conversion of immune suppressant. At 1 month, 6 month, and 1 year from the conversion of Immune suppressant (CNI to rapamune), the investigators performed tha analysis fo immune profile again. During the study period, the interval of the visit of subclinic and the kinds of laboratory test (Blood and urine test) would not change compared to before the start of this study.Phase:
N/AAccepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Seoul St. Mary's HospitalTreatments:
Calcineurin Inhibitors
Everolimus
Sirolimus
Criteria
Inclusion Criteria:1. Renal transplant recipient who has passed at least 10 years
2. No acute rejection episode during the previous 6 months
3. No change of prescription of immune suppressants
4. Normal allograft function (MDRD eGFR > 80 mL/min/1.73 m2)
5. Change of allograft function less than 10 % of baseline value durant the previous 1
year
6. No proteinuria and hematuria
Exclusion Criteria:
1. Patients who donut want to participate in this study
2. Patients who should continue immune suppressant due to another cause (e/g combined
autoimmune disease)