Overview

Study to Evaluate Organic Anion Transporting Polypeptide (OATP) Transporter-Mediated Drug-Drug Interactions Between Filgotinib and Statins as Probe Drugs in Healthy Participants

Status:
Completed

Trial end date:
2021-01-13

Target enrollment:

Participant gender:

Summary

The primary objective of this study is to evaluate the effect of filgotinib on a mixed organic anion transporting polypeptide/cytochrome P450 3A (OATP/CYP3A), OATP/ breast cancer resistance protein (BCRP), and OATP substrates using phenotypic probes.

Phase:

Phase 1

Details

Lead Sponsor:

Gilead Sciences

Collaborator:

Galapagos NV

Treatments:

Atorvastatin
Pravastatin
Rosuvastatin Calcium