Study to Evaluate Combination Treatment of MGCD0103 and Docetaxel (Taxotere®) for Subjects With Advanced Cancer Tumors
Status:
Terminated
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the combination of an experimental drug known as
MGCD0103 given along with an FDA-approved drug called docetaxel. This is a Phase 1 study that
will look at different doses of MGCD0103 given along with docetaxel in order to better
understand the effects (positive and negative) of this combination on the subject's body and
disease.
The study would like to find the following information:
- How long MGCD0103 and docetaxel stay in the subject's body;
- What effects, good and/or bad, MGCD0103 and docetaxel have on the subject and on his/her
cancer; and
- If the genetic and chemical make-up of the subject's blood cells and tumor cells play a
role in how you respond or do not respond to MGCD0103 and docetaxel.