Study to Demonstrate That Antibiotics Are Not Needed in Moderate Acute Exacerbations of COPD
Status:
Completed
Trial end date:
2019-06-05
Target enrollment:
Participant gender:
Summary
The ultimate goal is to reduce unnecessary antibiotic prescriptions which drive the
development of antibiotic resistance in the community. The primary objective of ABACOPD is to
demonstrate in a sufficiently sized clinical study that there is no relevant increase in the
"failure-rate" for patients with acute moderate exacerbations of COPD (AE-COPD) treated with
placebo instead of antibiotic treatment both on top of standard of care. A patient is
classified as treatment failure if additional antibiotic therapy is required during treatment
period or until the test of cure visit (TOC at day 30, primary endpoint).