Overview
Study on the Combination Regimen of Dexamethasone Ifosfamide Cisplatin Etoposide in Patients With NK/T Cell Lymphoma
Status:
Unknown status
Unknown status
Trial end date:
2010-12-01
2010-12-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of this study is to evaluate the efficacy and tolerability of the combination chemotherapy of DICE in the patients with NK/T cell lymphoma.Phase:
Phase 2Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Fudan UniversityTreatments:
Etoposide
Criteria
Inclusion Criteria:- Age range 18-75 years old
- Histological confirmed NK/T cell lymphoma
- ECOG performance status less than 2
- Life expectancy of more than 3 months
- None of major drugs in the trial (IFO,VP16,DDP) has been previously used
- Normal laboratory values: hemoglobin > 80 g/dl, neutrophil > 2×109/L, platelet >
100×109/L, serum creatine < 1.5×upper limitation of normal (ULN), serum bilirubin <
1.5×ULN, ALT and AST < 2.5×ULN
Exclusion Criteria:
- Pregnant or lactating women
- Serious uncontrolled diseases and intercurrent infection
- The evidence of CNS metastasis
- History of other malignancies except cured basal cell carcinoma of skin and carcinoma
in-situ of uterine cervix