Study on Opioid-free Anesthesia Protocol With S-ketamine and Propofol

• Status: Recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to observe the effects of opioid-free anesthesia with S-ketamine on perioperative hemodynamics in short surgical operations, and to explore the effects of esketamine on postoperative recovery time, postoperative incidence of nausea, vomiting and delirium, and postoperative pain.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The First Affiliated Hospital with Nanjing Medical University
• Treatments: Esketamine; Fentanyl; Ketamine

Criteria

Inclusion Criteria:

1. Aged from 18 years to 70 years

2. American society of anesthesiologists physical status classification I-II

3. Patients scheduled for Orthopedic, urological or general surgery （the duration of surgery less than 1 hour）

4. Willing to sign informed consent

Exclusion Criteria:

1. Allergic to anesthesia drugs;

2. Surgical history within the past 1 month;

3. Severe heart, lung, brain, liver or kidney diseases;

4. Neurological or mental diseases under treatment;

5. Inability to understand visual analog scale (VAS).