Study on Amino Acid Uptake in Brain Tumors

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the uptake of the amino acid O-(2-[F-18]Fluorethyl)-L-tyrosin (FET) in human brain tumors using positron emission tomography. A comparison to MRI and histopathological samples is used.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Muenster

Criteria

Inclusion Criteria:

• Patients with suspected primary brain tumors

• CT or MRI showing lesion of >= 2,5 cm

• Any age; parents informed consent in children available

• Karnofsky-Index >= 20 %

• Referral by Depts. of Neurology, Neuro-Oncology, Neurosurgery, or Pediatric Neurology at the UKM

• Biopsy and/or surgery planned

• Patient is able to lie during the PET scan for 50 minutes without moving • Patient must be able to give informed consent; signature must be present before the PET scan

Exclusion Criteria:

• Pregnancy or breast feeing

• Patients, who by psychiatric disease are not able to give informed consent

• Complete renal failure

• Inclusion to other studies according to § 23 of the German radiation protection law