Study of the Use of Misoprostol to Decrease Bleeding During a Myomectomy

• Status: Completed
• Trial end date: 2005-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study was done to determine if the use of a combination of preoperative rectal misoprostol 400µg used with intraoperative perivascular vasopressin is better than perivascular vasopressin used alone to decrease bleeding at myomectomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital of the West Indies
• Treatments: Arginine Vasopressin; Diuretics; Misoprostol; Vasopressins

Criteria

Inclusion Criteria:

• patients with symptomatic fibroids who desire future fertility and or who wish to maintain their uterus.

Exclusion Criteria:

• patients who have had previous myomectomy or previous pelvic surgery.

• patients who are severely anemic or who have significant medical conditions such as cardiac or pulmonary disease.

• patients who refuse to participate or give consent to the procedures. Patients with a known allergy to any of the study drugs.