Study of the Pharmacokinetics of Mycophenolate Mofetil in Patients Who Have Undergone Orthotopic Liver Transplantation
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
OBJECTIVES: I. Determine the effects of bile externalization and antibiotic gut sterilization
on the pharmacokinetics of mycophenolate mofetil in patients who have undergone orthotopic
liver transplantation.
II. Correlate serum concentrations of mycophenolic acid with inosine monophosphate
dehydrogenase activity in these patients.