Study of the Efficiency of Esophageal Dilation on Patient With Eosinophilic Esophagitis
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
This study is for patients who have had a food impaction and/or difficulty swallowing, who
are scheduled to have endoscopy, biopsy and possibly dilatation (stretching) of the
esophagus.
Standard treatment for people who have food impaction and difficulty swallowing is endoscopy
to view the esophagus, tissue biopsies of the lining of the esophagus for diagnosis, and drug
therapy including steroids and drugs used to treat reflux disease. Early dilatation or
stretching of the esophagus may be done at this time but not always. Some doctors prefer to
wait and see if the drugs are affective.
It is not known if dilating the esophagus early in treatment adds benefit. Therefore, we are
doing this study to compare the two methods of treatment. We will compare two groups: one
group will have dilatation performed during the first endoscopy and one group will not have
dilatation performed during endoscopy. We will see if dilatation helps prevent food impaction
and improves swallowing.
Another purpose of this study is to learn more about the causes of swallowing problems, thus
extra biopsies will be taken of the esophagus and store them for future research.
Phase:
N/A
Details
Lead Sponsor:
Vanderbilt University Vanderbilt University Medical Center