Overview

Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial)

Status:
Completed
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the hypothesis that chloroquine will reduce the ability of ductal carcinoma in situ (DCIS) to survive and spread. Participants will receive either chloroquine standard dose (500mg/week) or chloroquine low dose (250mg/week) for 1 month prior to surgical removal of the tumor.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Inova Health Care Services
Collaborators:
George Mason University
U.S. Army Medical Research and Development Command
U.S. Army Medical Research and Materiel Command
United States Department of Defense
University of Pittsburgh
University of Pittsburgh Medical Center
Treatments:
Chloroquine
Chloroquine diphosphate