Overview

Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery

Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this trial is to determine whether the water-soluble contrast (gastrografin) is more effective in the treatment of postoperative ileus than the conventional one.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hospital Universitari de Bellvitge
Criteria
Inclusion Criteria:

- All patients with postoperative ileus after colorectal surgery, defined as the
presence from the third postoperative day, abdominal distension, nausea, vomiting with
or without abdominal pain or discomfort by dilation of bowel loops, confirmed
radiology of the abdomen, and which are: Age > 18 years Patients undergoing laparotomy
or laparoscopy for the following variants of colorectal disease with or without stoma:

1. Neoplasia.

2. Inflammatory disease.

3. Diverticular disease. Patients who have been treated with standard PCA as
postoperative analgesia. Signed informed consent. Undergoing elective or
scheduled

Exclusion Criteria:

- Patient's refusal to sign informed consent

- Pregnancy or lactation

- Hypersensitivity to iodinated contrast agents (it´s the only contraindication to oral
Gastrografin) Presence of other problems that justify the etiology of postoperative
ileus:

1. Anastomotic leakages.

2. Mesenteric vascular disease.

3. Incarcerated hernias.

4. Intra-abdominal abscesses or collections.

5. Metabolic or electrolyte disturbances. If during the course of the study one of
the reasons previously cited as the etiology of postoperative ileus is present,
the patient shall also be excluded. Also excluded patients undergoing emergency
surgery.