Study of the Effect of Sitagliptin on Glucose (Sugar) Metabolism in Patients With Heart Failure
Status:
Completed
Trial end date:
2012-02-01
Target enrollment:
Participant gender:
Summary
This study will investigate the effects of sitagliptin, a medicine commonly used to treat
type 2 diabetes, on the utilization of glucose by the heart in patients with heart failure
which is not due to heart attacks. We hope to determine whether improving the heart's ability
to use glucose in the blood may help improve the function of the heart as well. If so, this
may suggest that even people who do not have frank diabetes but who do have heart failure may
benefit from using this medication.
This study will also investigate the effect of sitagliptin on the body's use of sugar, and of
the effect of sitagliptin on blood flow to the heart.