Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
The investigators hypothesize that, among non-hypertensive overweight and obese individuals,
treatment of vitamin D deficiency and lowering uric acid concentrations (by either xanthine
oxidase inhibition or increased renal excretion) will attenuate renin angiotensin system
(RAS) activation, improve endothelial function, and lower blood pressure.
Phase:
Phase 3
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Allopurinol Ergocalciferols Probenecid Uric Acid Vitamin D Vitamins