Study of Valproic Acid to Treat HIV Infected Adults
Status:
Terminated
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
A histone deacetylase (HDAC) inhibitor is a class of drug that interferes with the function
of HDAC, an enzyme that hides HIV within inactive CD4 cells. These drugs are normally used to
treat seizures and other nervous system problems but have been found to work against HIV. The
purpose of this study is to investigate the efficacy of valproic acid (VPA), an HDAC
inhibitor, in treating HIV infected adults using anti-HIV drugs.