Study of Temozolomide in the Treatment of Brain Metastasis From Non-small-cell Lung Cancer (Study P02143)
Status:
Terminated
Trial end date:
2003-01-30
Target enrollment:
Participant gender:
Summary
Brain metastases from solid tumors are diagnosed in more than 300,000 patients annually.
Nonsmall cell lung cancer accounts for the majority of CNS mets. Treatment with whole brain
radiation and steroids will improve neurologic symptoms in about 50% of patients although
survival is short. This study will test the safety and efficacy of temozolomide in
combination with radiation therapy in the treatment of patients with brain mets form nonsmall
cell lung cancer.