The purpose of this study is to test the safety of the compound sulforaphane that boosts the
activity of antioxidant genes in the body to combat oxidative stress. Oxidative stress has
been shown experimentally to play a role in kidney disease. This drug has been tested in
patients with breast cancer who have normal kidney function, but has never been tested in
patients with kidney disease.
In this study, the investigators will establish a safe dose for patients with chronic kidney
disease based on blood levels achieved in patients with normal kidney function.