Study of Stem Cell Transplantation for Hematologic Malignancies Using Clofarabine and Busulfan Regimen
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
The goals of the study are (Phase I) to determine the appropriate dose for Clofarabine with
Busulfan as a full-intensity conditioning (Clo/BU4 regimen) prior to transplant and then
(Phase II) to investigate the safety and effectiveness of this regimen as a conditioning for
stem cell transplant in the treatment of aggressive hematologic malignancies in subjects
where more conventional approaches are failing.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Michigan Cancer Center University of Michigan Rogel Cancer Center