Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis
Status:
Not yet recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to identify the most promising therapeutic strategy for patients
with granulomatosis with polyangiitis and inadequate response to standard of care therapy. It
will evaluate the efficacy to induce remission of three different salvage strategies
including: a combination of rituximab with addition of a conventional disease-modifying
antirheumatic drugs (either methotrexate, azathioprine or mycophenolate mofetil, but
preferentially methotrexate); tocilizumab; or abatacept.
Phase:
Phase 2
Details
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborators:
URC-CIC Paris Descartes Necker Cochin URC/CIC (Clinical Research Unit) Paris Descartes Necker-Cochin