Overview

Study of Rituximab and Bendamustine With or Without Brentuximab Vedotin for CD30 Positive Diffuse Large B-cell Lymphoma

Status:
Terminated
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
This is a randomized, open-label, multicenter, Phase 2 clinical trial designed to evaluate the efficacy and safety of brentuximab vedotin in combination with rituximab and bendamustine for the treatment of patients with relapsed or refractory CD30-positive diffuse large B-cell lymphoma (DLBCL) after failure of second-line salvage therapy or as second-line treatment in patients ineligible for autologous stem cell transplant (ASCT).
Phase:
Phase 2
Details
Lead Sponsor:
Seagen Inc.
Seattle Genetics, Inc.
Treatments:
Antibodies, Monoclonal
Bendamustine Hydrochloride
Brentuximab Vedotin
Rituximab