Overview Study of Rifaximin in Minimal Hepatic Encephalopathy Status: Completed Trial end date: 2012-12-01 Target enrollment: Participant gender: Summary Rifaximin therapy will improve brain functioning on MRI scanning and change the microbiome and metabolome. Phase: Phase 1/Phase 2 Details Lead Sponsor: Hunter Holmes Mcguire Veteran Affairs Medical CenterCollaborators: Bausch Health Americas, Inc.Valeant Pharmaceuticals International, Inc.Treatments: RifamycinsRifaximin