Study of Qiliqiangxin Capsule to Treat Dilated Cardiomyopathy
Status:
Completed
Trial end date:
2016-09-30
Target enrollment:
Participant gender:
Summary
The pathogenesis of dilated cardiomyopathy (DCM) leading to heart failure is closely
associated with autoimmunity dysfunction. A few studies represented that Qiliqiangxin
capsule, a Chinese medicine, could enhance heart function in chronic heart failure and
regulate the balance of TNF-a and IL-10 in myocardial infarction. In this study, to explore
the effects of Qiliqiangxin capsule on the improving heart function and immunoregulation in
patients with DCM, patients were recruited, anti-heart autoantibodies and some representative
cytokines were assayed by enzyme-linked immuno sorbent assay (ELISA), and the efficacy of
heart function improvement was compared between Qiliqiangxin capsule and placebo under the
standard treatment of DCM.
Phase:
Phase 4
Details
Lead Sponsor:
Huazhong University of Science and Technology
Collaborators:
China National Center for Cardiovascular Diseases China Three Gorges University, Yichang, China First Affiliated Hospital of Guangxi Medical University First Affiliated Hospital of Harbin Medical University First Affiliated Hospital Xi'an Jiaotong University Fudan University Guangxi Medical University Harbin Medical University Health Science Center of Xi’an Jiaotong University Henan Provincial People's Hospital Jingzhou Central Hospital Jining Medical University Ministry of Science and Technology of the People´s Republic of China RenJi Hospital Second Affiliated Hospital of Xi'an Jiaotong University Second Hospital of Shanxi Medical University Shandong Provincial Hospital Shanxi cardiovascular hospital Shanxi Medical University The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School The First Affiliated Hospital of Zhengzhou University The First Affiliated Hospital with Nanjing Medical University The Second Affiliated Hospital of Harbin Medical University Tianyou hospital affiliated to Wuhan University of Science and Technology Tongji Hospital Wuhan No.1 Hospital Wuhan Pu-Ai Hospital Wuhan Union Hospital, China Wuhan University Xiangyang Central Hospital Yunyang Medical College