Study of Postoperative ICC Analgesia

• Status: Recruiting
• Trial end date: 2023-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is to examine the analgesic effectiveness of continuous loco-regional analgesic application (ropivacaine) through surgically placed Intercostal Catheter (ICC) and to establish correctly this method as a possible standard of care in the postoperative analgesia after Video-assisted thoracoscopic surgery (VATS) anatomical lung resection.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Basel, Switzerland

Criteria

Inclusion Criteria:

• Informed Consent as documented by signature

• Patient undergoing video-assisted thoracoscopic anatomical resection of the lung under general anaesthesia for confirmed or anticipated Stage I lung cancer (UICC 8th edition)

• American Society of Anesthesiologists (ASA) physical status classes I to III

Exclusion Criteria:

• NRS while coughing > 0

• Previous ipsilateral thoracotomy or sternotomy

• Abdominal or contralateral thoracic surgery up to 6 months preoperatively

• Contraindications to the class of drugs under study, e.g. known hypersensitivity or allergy to class of drugs or the investigational product

• Contraindications to self-administration of opioids

• Women who are pregnant or breast feeding

• Chronic steroid therapy (e.g. Prednisone > 10mg/day for more than last 2 weeks before surgery)

• Chronic, daily pain therapy

• Congestive heart failure

• Liver insufficiency

• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,

• Participation in another study with investigational drug within the 30 days preceding and during the present study,

• Enrolment of the investigator, his/her family members, employees and other dependent person