Overview

Study of Oxaliplatin and Gemcitabine With or Without Bevacizumab to Treat Advanced Non-Small Cell Lung Cancer

Status:
Completed
Trial end date:
2008-03-01
Target enrollment:
Participant gender:
Summary
The combination of oxaliplatin and gemcitabine has proven activity in advanced non-small cell lung cancer (NSCLC). Due to its favorable toxicity profile, this combination is optimal for adding new agents. Bevacizumab is an anti-VEGF monoclonal antibody that has also shown favorable results in advanced NSCLC. This study will add bevacizumab to oxaliplatin and gemcitabine as first line treatment in patients with Stage IIIB and IV NSCLC.
Phase:
Phase 2
Details
Lead Sponsor:
Mt. Sinai Medical Center, Miami
Collaborators:
Genentech, Inc.
Sanofi-Synthelabo
Treatments:
Bevacizumab
Gemcitabine
Oxaliplatin