Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer
Status:
Recruiting
Trial end date:
2025-03-01
Target enrollment:
Participant gender:
Summary
Fusobacterium nucleatum (Fusobacterium nucleatum, Fn) has been identified as an independent
risk factor for recurrence of colorectal cancer. In this study, oral metronidazole would be
used to reduce the abundance of Fn in patients with high Fn, so as to explore whether oral
metronidazole can improve the efficacy of postoperative chemotherapy in patients with
colorectal cancer.
Phase:
Phase 2
Details
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Collaborators:
Fudan University Ruijin Hospital Shanghai Municipal Commission of Health and Family Planning Shanghai Shenkang Hospital Development Center Shanghai Zhongshan Hospital