Overview

Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors

Status:
Recruiting
Trial end date:
2023-09-02
Target enrollment:
Participant gender:
Summary
This is a phase 2 study of the combination of drugs olaparib and durvalumab for the treatment of isocitrate dehydrogenase or (IDH) mutated solid tumors. The purpose of this study is to assess the efficacy of the drug combination via overall response rate and overall disease control rate. It is believed that giving olaparib and durvalumab together would be more useful when given to patients with IDH-mutated solid tumors than giving each drug alone.
Phase:
Phase 2
Details
Lead Sponsor:
University Health Network, Toronto
Treatments:
Antibodies, Monoclonal
Durvalumab
Olaparib