Study of Nicotine for the Prevention of PONV

• Status: Terminated
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether nicotine is effective in the prevention of nausea and vomiting in non-smokers undergoing surgery

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Geneva
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Adults (18-80 years)

• ASA I-II, non-smokers (or ex-smokers who have not been smoking for more than 2 years)

• Undergoing elective surgery (ENT, abdominal, urological, gynaecological); and

• Consenting to take part in the study will be included.

Exclusion Criteria:

• Smokers (cigarette, pipe, cigar)

• Patients undergoing nicotine replacement therapy

• Prolonged postoperative intubation

• Postoperative nasogastric tube