Overview

Study of NMDA Antagonists and Neuropathic Pain

Status:
Completed
Trial end date:
2016-09-07
Target enrollment:
Participant gender:
Summary
The aim of this study is to evaluate if memantine or dextromethorphan gave in relay to ketamine maintains or induces a decrease of pain intensity. In clinical, after ketamine cure, clinicians have often difficulties to treat patients in order to maintain analgesia or suggest another treatment if analgesia induced by ketamine was not effective, which occurs in one quarter of patients. It will be very useful for monitoring of painful patients evaluate if memantine or dextromethorphan could be an effective therapeutic alternative in neuropathic pain treatment.
Phase:
Phase 2
Details
Lead Sponsor:
University Hospital, Clermont-Ferrand
Collaborators:
Dr Anne-Margot Duclot, Pain Clinic, Paris Rotschild Hospital
Dr Géraldine Brumauld de Montgazon, Pain Clinic, La Rochelle Hospital
Dr Malou Navez, Pain Clinic, Saint-Etienne Hopital
Dr Marc Sorel, Pain Clinic, Nemours Hospital
Dr Marie-Christine Crosmary/Dr Renato Colamarino, Pain Clinic, Vichy Hospital
Dr Mohamed El Ayadi, Pain Clinic, Issoire Hospital
Dr Monique Belon, Pain Clinic, Aurillac Hospital
Treatments:
Antitussive Agents
Dextromethorphan
Ketamine
Memantine