Study of Methyl Aminolaevulinate Photodynamic Therapy With and Without Er:YAG Laser in Actinic Cheilitis
Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
Methyl aminolaevulinate photodynamic therapy (MAL-PDT) is advantageous in that it has few
cosmetic side effects and minimises patient discomfort. However, its relatively low efficacy
prevents its application to the treatment of actinic cheilitis(AC). Er:YAG ablative
fractional laser (AFL) treatment removes the stratum corneum to increase MAL uptake and may
improve efficacy. However, no studies have directly compared the efficacy of MAL-PDT with and
without Er:YAG AFL in treating AC