Study of Metformin With Simvastatin for Men With Prostate Carcinoma
Status:
Withdrawn
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find out whether the two drugs used in the study, metformin
and simvastatin, can slow down the speed of rise of prostate specific antigen (PSA) or stop
its rise or even bring the level down.
Recently, scientists noticed that men who take metformin to treat their high blood sugar or
simvastatin to treat their high cholesterol are less likely to develop prostate cancer. Also,
scientists found that, when these drugs are used in preclinical studies, they can slow down
the growth of the prostate cancer cells. This study will try to find out whether these drugs
can actually slow down the growth of prostate cancer in men.