Study of Mechanisms of Anovulation in Polycystic Ovary Syndrome
Status:
Completed
Trial end date:
2007-01-01
Target enrollment:
Participant gender:
Summary
We previously hypothesized that the excess of Anti-Mullerian Hormone (AMH) at the level of
ovarian selectable follicles could be involved in the follicular arrest of Polycystic Ovary
Syndrome (PCOS), mainly through inhibition of FSH effect on aromatase expression.In this
study, we plan to investigate whether a drop in the serum AMH level would be concomitant to
the appearance of a dominant follicle induced by administration of mild amounts of exogenous
FSH in women with PCOS.