Overview

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Status:
Completed
Trial end date:
2021-01-25
Target enrollment:
Participant gender:
Summary
This study is for newly diagnosed WHO Grade IV malignant glioma patients to determine whether an investigational drug known as marizomib (MRZ) will improve the treatment of newly diagnosed glioblastoma patients by delaying the growth of the cancer, reducing the size of the tumor, and/or improving survival. Marizomib (MRZ) is being added to standard-of-care treatments of radiotherapy (RT), temozolomide (TMZ), and Optune.
Phase:
Phase 1
Details
Lead Sponsor:
Celgene
Triphase Research and Development I Corporation
Collaborator:
Triphase
Treatments:
Dacarbazine
Temozolomide