Study of Lenalidomide in Combination With RICE With Lenalidomide Maintenance Post-Auto Transplant for DLBCL
Status:
Unknown status
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
The standard of care therapy for DLBCL in the relapsed setting is RICE with the plan for the
patient to proceed to transplant. This protocol will add Revlimid to the first 7 days of the
RICE therapy and again after transplant as maintenance. To improve over all outcome and
survival.
Hypothesis is that combining lenalidomide with standard of care (RICE) may increase overall
response rate thus increasing the number of patients able to proceed with autologous stem
cell transplant. This in turn may translate into improved overall survival and progression
free survival.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Hackensack Meridian Health Hackensack University Medical Center