Study of Lamotrigine Treatment of Affective Instability in Borderline Personality Disorder

• Status: Completed
• Trial end date: 2007-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This study investigates the hypothesis that instability in mood in patients with borderline personality disorder will respond the mood stabilizing medication lamotrigine.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mclean Hospital
• Collaborator: GlaxoSmithKline
• Treatments: Anticonvulsants; Lamotrigine

Criteria

Inclusion Criteria:

• Clinical Diagnosis of Borderline Personality Disorder with high levels of emotional instability

Exclusion Criteria:

• Clinical diagnosis of Bipolar Disorder

• Clinical diagnosis of psychiatric disorder related to general medical condition

• Clinical diagnosis of substance abuse disorder within the last 60 days

• Clinical diagnosis of psychotic disorder

• Previous treatment with lamotrigine

• Pregnancy or nursing

• Currently hospitalized

• Active suicidal or homicidal ideation