Study of Intravenous Aflibercept in Combination With FOLFIRI in Japanese Patients With Metastatic Colorectal Cancer
Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
The primary objective is to determine the dose of aflibercept to be further studied in
combination with irinotecan/5-fluorouracil/isovorin (FOLFIRI) in Japanese patients with
metastatic colorectal cancer.
Secondary objectives of this study are to assess the safety profile of aflibercept, to
determine the pharmacokinetics of aflibercept, to make a preliminary assessment of antitumor
effects.