Study of Interventional Pulmonologic Treatment of Benign Central Airway Fibrotic Stricture

• Status: Unknown status
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy and safety of four interventional pulmonology techniques for the treatment of fibrotic central airway stricture.

The four techniques are：

• balloon dilation

• balloon dilation plus cryotherapy

• balloon dilation plus spiculiform electrosurgery

• balloon dilation plus mitomycin C injection

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tang-Du Hospital
• Collaborators: Changhai Hospital; China Meitan General Hospital; Micro-Tech (Nanjing) Co., Ltd.; The First Affiliated Hospital of Guangzhou Medical University; Xinqiao Hospital of Chongqing
• Treatments: Mitomycin; Mitomycins

Criteria

Inclusion Criteria:

• tracheal incision,intubation or bronchial tuberculosis caused central airway fibrotic stenosis

• the degree of stenosis is above 50%

• estimated survival duration is longer than 3 months

• recieved no treatment one month before

• can understand the statement informed consent

• agree to enroll in the study

Exclusion Criteria:

• older than 70 years or younger than 18 years

• not fibrotic stenosis

• not central airway stenosis

• existence of lumina collapse or twisting

• severe arrhythmia, myocardial ischemia or hypertensive crisis

• coagulation disorders

• existence of severe organ disfunction

• allergic to anesthesia drugs

• refuse to participate the study