Overview

Study of Immunotherapy in Combination With Chemotherapy in HER2-negative Inflammatory Breast Cancer

Status:
Recruiting
Trial end date:
2025-04-30
Target enrollment:
Participant gender:
Summary
This phase II multicentre randomized open-label study will assess the safety and efficacy of Pembrolizumab in combination with standard chemotherapy in inflammatory breast cancer. Pembrolizumab will be administered every 3 weeks during the neoadjuvant chemotherapy. Tissue and blood samples will be collected pre- and post-treatment for translational research.
Phase:
Phase 2
Details
Lead Sponsor:
Institut Paoli-Calmettes
Collaborators:
MSD France
Oncodistinct
Treatments:
Albumin-Bound Paclitaxel
Cyclophosphamide
Paclitaxel
Pembrolizumab