Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19
Status:
Terminated
Trial end date:
2021-04-01
Target enrollment:
Participant gender:
Summary
Ideal new treatments for Novel Coronavirus-19 (COVID-19) would help halt the progression
disease in patients with mild disease prior to the need for artificial respiration
(ventilators), and also provide a rescue treatment for patients with severe disease, while
also being affordable and available in quantities sufficient to treat large numbers of
infected people. Low doses of Naltrexone, a drug approved for treating alcoholism and opiate
addiction, as well as Ketamine, a drug approved as an anesthetic, may be able to interrupt
the inflammation that causes the worst COVID-19 symptoms and prove an effective new
treatment. This study will investigate their effectiveness in a randomized, blinded trial
versus standard treatment plus placebo.